Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003o015 | SRF Post-Doctoral Prize Session | SRF2016

The crosstalk between Nodal and Tumor Necrosis factor alpha during luteolysis establishment in the mare

Galvao Antonio , Staszkiewicz Joanna , Thomas Karolina , Rebordao Maria , Skarzynski Dariusz , Ferreira-Dias Graca

Introduction: In the absence of pregnancy, the resumption of a new estrous cycle is assured by functional and structural regression of the corpus luteum (CL). We have recently characterized the involvement of Nodal, a morphogen from transforming growth factor beta superfamily, on functional luteolysis in the mare (Galvao et al, 2015 Endocrinology, 157:858–871). Also, tumor necrosis factor α (TNF) has been reported to mediate both functional and structural luteal regr...